The report from the Court of Auditors, published on Monday, April 27, 2026, forcefully reiterates a reality that is still too often underestimated: the quality of care is not measured solely by the excellence of the procedures, but also by the ability to prevent associated risks.
The Nosocomial infectionswhich affect approximately 6% of hospitalized patients and cause nearly 4,000 deaths per yearThese infections are a prime example. They reveal a structural weakness: they are often linked to the patient's own bacteria, made dangerous by the care itself and aggravated by the rise in [unclear - possibly "infection"].antibiotic resistanceWhen antibiotics stop working, all of modern medicine – surgery, intensive care, oncology – falters.
Faced with this threat, the response cannot be solely organizational or preventive: it must also be scientific.
At the Pasteur Institute in Lille, our teams are fully mobilized to understand the mechanisms of resistance, but above all to discover new classes of antibioticscapable of circumventing these resistances.
To achieve this, the Pasteur Institute of Lille inaugurated its Drug Discovery Center : 1,500 m² of state-of-the-art laboratories dedicated to therapeutic innovation. Thanks to the largest chemical library in Europe and the expertise of its medicinal chemists, this center enables the synthesis of novel anti-infective molecules. This is the case with...Alpibectir, a promising new antibiotic developed to combat resistance to tuberculosis treatments.
At the same time, radically new approaches are emerging, such as exploration of extreme environments, particularly in the deep sea, to identify antimicrobial peptides with unique properties. This research, at the frontier of science and exploration, also paves the way for the antibiotics of tomorrow.
This report is therefore more than just an observation: it is a call to accelerate.
Accelerate research, innovation, and their transformation into concrete treatments.to make the fight against nosocomial infections and antibiotic resistance a central pillar of quality of care.
