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Directeur :
Groupe Avenir INSERM
Associé à l'U801
Institut Pasteur
de Lille
Rattachée à l'IFR 142
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| Microbiologie |
Muqueuse. Bacterie. Immunité innée. Cellule dendritique. Immunité adaptative. |
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Foligne B, Zoumpopoulou G, Dewulf J, Ben Younes A, Chareyre F, Sirard JC, Pot B, Grangette C.
A key role of dendritic cells in probiotic functionality.
PLoS ONE, 2007, 2:e313. |
Guo A, Lasaro MA, Sirard JC, Kraehenbuhl JP, Schifferli DM.
Adhesin-dependent binding and uptake of Salmonella enterica serovar Typhimurium by dendritic cells.
Microbiology, 2007, 153:1059-1069. |
Sirard JC, Vignal C, Dessein R, Chamaillard M.
Nod-Like Receptors as watchdogs for an immune response towards microbial and dangerous signals.
PLoS Pathogens, 2007, in press. |
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Didierlaurent A, Brissoni B, Velin D, Aebi N, Tardivel A, Kaslin E, Sirard JC, Angelov G, Tschopp J, Burns K.
Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide.
Mol Cell Biol, 2006, 26:735-742. |
Le Borgne M, Etchart N, Goubier A, Lira SA, Sirard JC, Van Rooijen N, Caux C, Ait-yahia S, Vicari A, Kaiserhian D, Dubois B.
Dentritic cell rapidly recruited into epithelial tissues via CCR6/CCL20 are resonsible for CD8(+) T Cell crosspriming in vivo.
Immunity, 2006, 24:191-201. |
Luu RA, Gurnani K, Dudani R, Kammara R, Van Faassen H, Sirard JC, Krishnan L, Sad S.
Delayed expansion and contraction of CD8+ T Cell Response during infection with virulent Salmonella typhimurium.
J Immunol, 2006, 177:1516-1525. |
Rumbo M, Nempont C, Kraehenbuhl JP, Sirard JC.
Mucosal interplay among commensal and pathogenic bacteria : lessons from flagellin and Tolk-like receptor 5.
FEBS Lett, 2006, 580:2976-2984. |
Sirard JC, Bayardo M, Didierlaurent A.
Pathogen-specific TLR signaling in mucosa : mutual contribution of microbial TLR agonists and virulence factors.
Eur J Immunol, 2006, 36:260-263. |
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